First Clue

Second Clue

Answer

Most of the first part (top section, painted in black) of the sign shouldn't present any problems for you. The one word you might find difficult is the last one; the key hint is that the first letter in this word is an independent vowel...

The second part of the sign (the lower section, painted in red) is set up like a proverb (your key here is the "equal" sign), and its subject matter is directly related to the subject of the upper, main portion of the sign.